What Are the Side Effects of Mounjaro?

Mounjaro, also known as tirzepatide, is an innovative prescription medication that has shown great potential in promoting weight loss in clinical trials. Due to rising levels of obesity, and therefore increasing need for treatments, many people are rushing to try game-changing medications like Mounjaro to solve their problems. 

But like any medication, Mounjaro may have side effects that users should be aware of. Here at Bodyline, we at the fore of the latest obesity medical treatment news, and believe it is vital to ensure those interested are given all the information. That’s why we’ll be exploring the possible side effects of Mounjaro and provide important information for individuals considering this medication as part of their weight loss journey.

Understanding Mounjaro

Mounjaro was originally created by pharmaceutical company Eli Lilly for the treatment of type-2 diabetes, however clinical trials have shown incredible weight loss results in over 85% of users. It is an injectable therapy administered once-weekly containing the active ingredient tirzepatide. 

Mounjaro has two incretin hormones and it is classified as a ‘dual-agonist’.  This double agonist approach seems to cause people who use Mounjaro weekly injections to lose even more weight than those who use a single-agonist medication.  These receptors stimulate hormones that control blood sugar levels and reduce appetite, triggering weight loss.  The receptors are known as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).

In the UK, as of November 2023 Mounjaro has been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) to be prescribed as a weight loss management treatment. It will be available to those who have a BMI of over 30 and those with a BMI of over 27 but suffer with weight related health problems like prediabetes or high blood pressure.

Bodyline is at the forefront of providing the latest obesity treatment options, as we continue to offer safe, effective, and sustainable medical weight loss programmes.


Contact Bodyline today to find out more about our safe and effective weight loss programmes and range of treatment options.

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Common Side Effects

Like other single hormone, GLP-1 receptor agonists, Mounjaro can cause gastrointestinal side effects. Ensuring safety while using weight loss medications should be prioritised, which is why it is vital to use it within a fully clinically supported and holistic medical weight loss programme with clinics like Bodyline. 

Our experienced and qualified healthcare professionals can monitor side effects and alter prescriptions and dosages where needed, putting emphasis on safety and wellness all throughout the weight loss journey. Though these side effects are generally mild and tend to subside over time, some people can have adverse experiences. 

The most commonly reported gastrointestinal side effects include:

  1. Nausea: Some users may experience feelings of nausea, which may range from mild to moderate. This side effect is usually temporary and fades as the body adjusts to the medication.
  2. Constipation: Mounjaro can occasionally cause constipation. It is important to maintain hydration and consume a diet rich in fibre to help alleviate this side effect. Due to the medications impact on slowing digestion, it is also vital to ensure you are adjusting your daily food intake, as high-sugar food can worsen the impact of this side effect.
  3. Diarrhoea: In some cases, users may experience diarrhoea while taking Mounjaro. This side effect is usually temporary and should improve with time, but ensure you drink plenty of water as diarrhoea can be dehydrating.
  4. Heartburn: Heartburn or acid reflux may occur as a result of taking Mounjaro. It is recommended to avoid spicy and acidic foods, eat smaller meals, and maintain an upright posture after eating to minimize this side effect.
  5. Contraceptive efficacy: obese or overweight women who are taking the oral contraceptive pill are advised to use barrier methods like condoms to prevent pregnancy, as the MHRA warns that Mounjaro may affect how well the contraceptive pill works in these patients.

There are no foods to avoid while taking Mounjaro or WeGovy, but it is advisable to eat slower, consume smaller portions, and limit ultra-processed foods that are high in sugar and saturated fats in order to see the best outcomes and limit side effects.

Rare Side Effects

While rare, some individuals may experience more severe side effects while taking Mounjaro. These side effects should be promptly reported to a healthcare professional. Rare side effects may include:

Hypoglycaemia: Mounjaro may lower blood sugar levels, leading to hypoglycaemia (low blood sugar). Symptoms of hypoglycaemia include dizziness, confusion, shakiness, and sweating. It is important to be part of a fully supported medical weight loss programme to monitor your health and alter your treatment as and when you need.

Pancreatitis: Although rare, Mounjaro has been associated with cases of pancreatitis, which is inflammation of the pancreas. Symptoms may include severe abdominal pain, nausea, and vomiting. If these symptoms occur, immediate medical attention should be sought.

Thyroid Cancer: There have not been any human instances of thyroid cancer in the use of Mounjaro, but in trials there have been cases of it in animal trials. If you notice any lumps around your neck or trouble with breathing or swallowing, it is vital you speak to your doctor as soon as possible.

Safety Precautions

It is crucial to use Mounjaro under proper medical supervision. Weight loss medications, including Mounjaro, should only be prescribed when a clinical triage has been undertaken and part of a comprehensive weight loss program that includes a reduced-calorie diet, increased physical activity, and lifestyle modifications. Regular monitoring and follow-up with a healthcare professional are essential to ensure the proper use and safety of injectable therapies like Mounjaro.

If you are interested to find out more about Mounjaro or other more appropriate weight loss medications consult with Bodyline who can assess your specific situation and provide personalized recommendations. They will evaluate your medical history, current medications, and overall health to determine the suitability of Mounjaro for you.

Continued support across the bespoke weight loss programme will see side effects closely monitored, with advice and guidance from experienced nurses who can alter dosage, prescription, and offer lifestyle advice. This ensures that you can achieve the results you want safely, effectively, and sustainably.At Bodyline, our dedicated weight loss specialists prioritize your well-being. We offer personalized weight loss programmes that include medical supervision and ongoing support. Contact us today at 0800 995 6036 or through our online contact form to learn more about Mounjaro and how it may be integrated into our comprehensive weight loss program.

About the author

Picture of Sally-Ann Turner

Sally-Ann Turner

I am founder and Managing Director of Bodyline, with over two decades of experience in the healthcare and wellness industries. I combine a deep understanding of medical wellness with a passion for science-backed health solutions and future-focused care. I have a specialist interest in developing gold standard clinical services for medical weight loss, including the latest GLP-1 medications, hormone health, and low-dose naltrexone (LDN) treatments.

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