How Weight Loss Injections Help You Remain in a Calorie Deficit

Losing weight can be a challenging journey, and many individuals struggle to achieve their desired results despite their best efforts. One crucial aspect of weight loss is creating a calorie deficit, which means consuming fewer calories than your body needs to maintain its current weight.

While traditional methods of calorie deficit, such as diet and exercise, are effective for many people, some individuals may find it challenging to sustain a calorie deficit or experience slower progress. In such cases, medical weight loss injections can be a game-changer.

Here at Bodyline, we like to de-mystify the science and debunk the myths about effective weight loss, that’s why we’ve put together this explainer to help you understand the benefits of a calorie deficit for weight loss, and how weight loss injections may be able to help your weight loss journey.

Understanding Calorie Deficit

Before we delve into how weight loss injections can assist in maintaining a calorie deficit, let’s first understand the concept of a calorie deficit. Calories are a unit of measurement used to quantify the energy content in food and beverages. When we consume more calories than our body needs, the excess energy is stored as fat, leading to weight gain.

On the other hand, when we consume fewer calories than our body requires, it creates an energy imbalance, prompting the body to tap into its fat stores for additional energy. This is known as a calorie deficit and is the key to weight loss.

Challenges in Maintaining a Calorie Deficit

While the concept of a calorie deficit seems straightforward, many people encounter difficulties in maintaining it. Several factors can make it challenging to adhere to a reduced-calorie diet and sustain weight loss.

These factors include genetic predispositions, metabolic rate variations, hormonal imbalances, and lifestyle factors. Additionally, some individuals may struggle with portion control, mindful eating, and sustaining the caloric deficit long enough to see sustainable results.

Bernie Murphy, Head of Clinical Services at Bodyline explains why calorie deficits, when done wrong, cannot be maintained:

“There is a common misconception that when you’re significantly overweight you should go into a dramatic calorie deficit. Now yes, you will lose weight short term and you’ll think it’s working. But hormonally, you are physiologically causing harm, because your body isn’t designed to do that. It will think it’s gone into starvation mode, or in hibernation. This will mean it starts to store the fat and instead burn your muscle, causing them to feel weak, and tired, and make you more likely to binge.”

The Role of Weight Loss Injections

Weight loss injections administer medications that activate GLP-1 or combined GLP-1 GIP receptors in the body, these medications are known as receptor agonists.

The medications currently available to be prescribed for the treatment of obesity in the UK are:

Tirzepatide mimics the effects of two hormones that are naturally produced in the body, these are glucose-dependent insulinotropic polypeptides (GIP) and glucagon-like-peptides 1 (GLP-1) receptor agonists.  The dual hormone is proven to support greater weight loss. Semaglutide and Liraglutide just mimics GLP-1 receptor agonists.

Both GLP-1s and GIPs are released in the gut and help individuals achieve weight loss by addressing multiple aspects of the weight management process.  By mimicking the effects of GLP-1 and GIP, these injections encourage the body to:

  • Stimulate insulin secretion, a hormone that prevents blood sugar levels getting too high
  • Inhibit glucagon secretion, a hormone that prevents blood sugar levels going too low
  • Promotes the feeling of fullness and satiety
  • Regulate appetite and food intake

By suppressing appetite, increasing metabolism, and promoting a feeling of fullness, weight loss injections enable individuals to consume fewer calories, ultimately leading to weight loss.

It is important to note that weight loss injections are only available to eligible patients through a prescription. Any sellers offering weight loss injections or “skinny jabs” online without health checks, prescriptions, or ongoing support and side effect monitoring should be avoided as this could be a scam and a danger to health.

If you’re worried about how to know which skinny jabs are legitimate, read this handy guide we put together.


Contact Bodyline today to find out more about our safe and effective weight loss programmes and range of treatment options.

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Benefits of Weight Loss Injections

Weight loss injections offer several benefits that contribute to their effectiveness in maintaining a calorie deficit:

1. Appetite Suppression

One of the primary mechanisms of weight loss injections is appetite suppression. By activating GLP-1 or GLP-1 GIP receptors in the body, these injections reduce hunger and food cravings, making it easier to adhere to a reduced-calorie diet. Individuals feel satisfied with smaller portions and are less likely to engage in emotional or binge eating.

2. Regulation of Blood Sugar Levels

GLP-1 and GIP receptor agonists, hormones in weight loss injections, help regulate blood sugar levels. By controlling blood sugar spikes and promoting insulin secretion, these injections contribute to overall metabolic health. Stable blood sugar levels reduce cravings for sugary and high-calorie foods, facilitating adherence to a calorie deficit.

3. Support for Lifestyle Changes

Medical weight loss programmes that incorporate weight loss injections should provide comprehensive support for lifestyle changes. Bodyline programmes offer guidance on nutrition, exercise, and behaviour modification, helping individuals adopt healthier habits and sustain weight loss over time. The combination of weight loss injections and a holistic approach increases the chances of long-term success.

Personalised Approach to Weight Loss

It is important to note that weight loss injections are not a one-size-fits-all solution. Each individual’s weight loss journey is unique, and personalized guidance is crucial for optimal results. Working with healthcare professionals who specialize in medical weight loss, such as Bodyline, ensures that individuals receive tailored treatment plans based on their specific needs and goals.

The Bodyline Difference

Bodyline is a leading provider of medical weight loss programmes in the UK, offering personalised solutions to help individuals achieve their weight loss goals. Our experienced healthcare professionals specialise in weight management and provide ongoing support and guidance throughout the weight loss journey.

Our Trustpilot reviews speak for themselves, and with 17 years of experience in the obesity treatment sector, you can be sure we are experts in medical weight loss.

Bodyline’s weight loss programmes provide comprehensive support, tailored treatment plans, and ongoing guidance to help individuals on their weight health journey. Remember, prioritising weight health is an investment in your overall well-being and quality of life.

If you’re ready to take control of your weight loss goals, contact Bodyline today at 0800 995 6036 or fill in an online contact form for a call back to learn more about our personalised weight loss programmes.

About the author

Picture of Sally-Ann Turner

Sally-Ann Turner

I am founder and Managing Director of Bodyline, with over two decades of experience in the healthcare and wellness industries. I combine a deep understanding of medical wellness with a passion for science-backed health solutions and future-focused care. I have a specialist interest in developing gold standard clinical services for medical weight loss, including the latest GLP-1 medications, hormone health, and low-dose naltrexone (LDN) treatments.

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